Pesquisa | BVS IEC

1.

G-CSF drives autoinflammation in APLAID.

Mulazzani, Elisabeth; Kong, Klara; Aróstegui, Juan I; Ng, Ashley P; Ranathunga, Nishika; Abeysekera, Waruni; Garnham, Alexandra L; Ng, Sze-Ling; Baker, Paul J; Jackson, Jacob T; Lich, John D; Hibbs, Margaret L; Wicks, Ian P; Louis, Cynthia; Masters, Seth L.

Nat Immunol ; 24(5): 814-826, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-36997670

2.

Blockade of the co-inhibitory molecule PD-1 unleashes ILC2-dependent antitumor immunity in melanoma.

Jacquelot, Nicolas; Seillet, Cyril; Wang, Minyu; Pizzolla, Angela; Liao, Yang; Hediyeh-Zadeh, Soroor; Grisaru-Tal, Sharon; Louis, Cynthia; Huang, Qiutong; Schreuder, Jaring; Souza-Fonseca-Guimaraes, Fernando; de Graaf, Carolyn A; Thia, Kevin; Macdonald, Sean; Camilleri, Mary; Luong, Kylie; Zhang, Shengbo; Chopin, Michael; Molden-Hauer, Tristan; Nutt, Stephen L; Umansky, Viktor; Ciric, Bogoljub; Groom, Joanna R; Foster, Paul S; Hansbro, Philip M; McKenzie, Andrew N J; Gray, Daniel H D; Behren, Andreas; Cebon, Jonathan; Vivier, Eric; Wicks, Ian P; Trapani, Joseph A; Munitz, Ariel; Davis, Melissa J; Shi, Wei; Neeson, Paul J; Belz, Gabrielle T.

Nat Immunol ; 22(7): 851-864, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-34099918

3.

SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition.

Nguyen, Tan A; Smith, Blake R C; Tate, Michelle D; Belz, Gabrielle T; Barrios, Marilou H; Elgass, Kirstin D; Weisman, Alexandra S; Baker, Paul J; Preston, Simon P; Whitehead, Lachlan; Garnham, Alexandra; Lundie, Rachel J; Smyth, Gordon K; Pellegrini, Marc; O'Keeffe, Meredith; Wicks, Ian P; Masters, Seth L; Hunter, Craig P; Pang, Ken C.

Immunity ; 47(3): 498-509.e6, 2017 09 19.

Artigo em Inglês | MEDLINE | ID: mdl-28916264

4.

G-CSF - A double edge sword in neutrophil mediated immunity.

Martin, Katherine R; Wong, Huon L; Witko-Sarsat, Véronique; Wicks, Ian P.

Semin Immunol ; 54: 101516, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-34728120

5.

How toxic is an old friend? A review of the safety of hydroxychloroquine in clinical practice.

Fairley, Jessica L; Nikpour, Mandana; Mack, Heather G; Brosnan, Maria; Saracino, Amanda M; Pellegrini, Marc; Wicks, Ian P.

Intern Med J ; 53(3): 311-317, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-35969110

6.

Emerging roles for IL-11 in inflammatory diseases.

Fung, Ka Yee; Louis, Cynthia; Metcalfe, Riley D; Kosasih, Clara C; Wicks, Ian P; Griffin, Michael D W; Putoczki, Tracy L.

Cytokine ; 149: 155750, 2022 01.

Artigo em Inglês | MEDLINE | ID: mdl-34689057

7.

Leukocyte Tetraspanin CD53 Restrains α₃ Integrin Mobilization and Facilitates Cytoskeletal Remodeling and Transmigration in Mice.

Yeung, Louisa; Anderson, Jeremy M L; Wee, Janet L; Demaria, Maria C; Finsterbusch, Michaela; Liu, Yuxin S; Hall, Pam; Smith, Brodie C; Dankers, Wendy; Elgass, Kirstin D; Wicks, Ian P; Kwok, Hang Fai; Wright, Mark D; Hickey, Michael J.

J Immunol ; 205(2): 521-532, 2020 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-32532837

8.

TNF and IL-1 Play Essential but Temporally Distinct Roles in Driving Cardiac Inflammation in a Murine Model of Kawasaki Disease.

Stock, Angus T; Jama, Hamdi A; Hansen, Jacinta A; Wicks, Ian P.

J Immunol ; 202(11): 3151-3160, 2019 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-30996002

9.

The Selective Expansion and Targeted Accumulation of Bone Marrow-Derived Macrophages Drive Cardiac Vasculitis.

Stock, Angus T; Collins, Nicholas; Smyth, Gordon K; Hu, Yifang; Hansen, Jacinta A; D'Silva, Damian B; Jama, Hamdi A; Lew, Andrew M; Gebhardt, Thomas; McLean, Catriona A; Wicks, Ian P.

J Immunol ; 202(11): 3282-3296, 2019 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-31004011

10.

The Pyroptotic Cell Death Effector Gasdermin D Is Activated by Gout-Associated Uric Acid Crystals but Is Dispensable for Cell Death and IL-1ß Release.

Rashidi, Maryam; Simpson, Daniel S; Hempel, Anne; Frank, Daniel; Petrie, Emma; Vince, Angelina; Feltham, Rebecca; Murphy, Jane; Chatfield, Simon M; Salvesen, Guy S; Murphy, James M; Wicks, Ian P; Vince, James E.

J Immunol ; 203(3): 736-748, 2019 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-31209100

11.

SIDT1 Localizes to Endolysosomes and Mediates Double-Stranded RNA Transport into the Cytoplasm.

Nguyen, Tan A; Smith, Blake R C; Elgass, Kirstin D; Creed, Sarah J; Cheung, Shane; Tate, Michelle D; Belz, Gabrielle T; Wicks, Ian P; Masters, Seth L; Pang, Ken C.

J Immunol ; 202(12): 3483-3492, 2019 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-31061008

12.

Extracellular Vesicles in Synovial Fluid from Rheumatoid Arthritis Patients Contain miRNAs with Capacity to Modulate Inflammation.

Foers, Andrew D; Garnham, Alexandra L; Chatfield, Simon; Smyth, Gordon K; Cheng, Lesley; Hill, Andrew F; Wicks, Ian P; Pang, Ken C.

Int J Mol Sci ; 22(9)2021 May 06.

Artigo em Inglês | MEDLINE | ID: mdl-34066338

13.

Monosodium Urate Crystals Generate Nuclease-Resistant Neutrophil Extracellular Traps via a Distinct Molecular Pathway.

Chatfield, Simon M; Grebe, Kathrin; Whitehead, Lachlan W; Rogers, Kelly L; Nebl, Thomas; Murphy, James M; Wicks, Ian P.

J Immunol ; 200(5): 1802-1816, 2018 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-29367211

14.

Dysregulated IL-1ß-GM-CSF Axis in Acute Rheumatic Fever That Is Limited by Hydroxychloroquine.

Kim, Man Lyang; Martin, William J; Minigo, Gabriela; Keeble, Joanne L; Garnham, Alexandra L; Pacini, Guido; Smyth, Gordon K; Speed, Terence P; Carapetis, Jonathan; Wicks, Ian P.

Circulation ; 138(23): 2648-2661, 2018 12 04.

Artigo em Inglês | MEDLINE | ID: mdl-30571257

15.

NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology.

Schlenner, Susan; Pasciuto, Emanuela; Lagou, Vasiliki; Burton, Oliver; Prezzemolo, Teresa; Junius, Steffie; Roca, Carlos P; Seillet, Cyril; Louis, Cynthia; Dooley, James; Luong, Kylie; Van Nieuwenhove, Erika; Wicks, Ian P; Belz, Gabrielle; Humblet-Baron, Stéphanie; Wouters, Carine; Liston, Adrian.

Ann Rheum Dis ; 78(3): 342-349, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30552177

16.

Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis.

Dragoljevic, Dragana; Kraakman, Michael J; Nagareddy, Prabhakara R; Ngo, Devi; Shihata, Waled; Kammoun, Helene L; Whillas, Alexandra; Lee, Man Kit Sam; Al-Sharea, Annas; Pernes, Gerard; Flynn, Michelle C; Lancaster, Graeme I; Febbraio, Mark A; Chin-Dusting, Jaye; Hanaoka, Beatriz Y; Wicks, Ian P; Murphy, Andrew J.

Eur Heart J ; 39(23): 2158-2167, 2018 06 14.

Artigo em Inglês | MEDLINE | ID: mdl-29905812

17.

Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface.

Moghaddas, Fiona; Zeng, Ping; Zhang, Yuxia; Schützle, Heike; Brenner, Sebastian; Hofmann, Sigrun R; Berner, Reinhard; Zhao, Yuanbo; Lu, Bingtai; Chen, Xiaoyun; Zhang, Li; Cheng, Suyun; Winkler, Stefan; Lehmberg, Kai; Canna, Scott W; Czabotar, Peter E; Wicks, Ian P; De Nardo, Dominic; Hedrich, Christian M; Zeng, Huasong; Masters, Seth L.

J Allergy Clin Immunol ; 142(6): 1956-1967.e6, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-29778503

18.

Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis.

Campbell, Ian K; Leong, David; Edwards, Kirsten M; Rayzman, Veronika; Ng, Milica; Goldberg, Gabrielle L; Wilson, Nicholas J; Scalzo-Inguanti, Karen; Mackenzie-Kludas, Charley; Lawlor, Kate E; Wicks, Ian P; Brown, Lorena E; Baz Morelli, Adriana; Panousis, Con; Wilson, Michael J; Nash, Andrew D; McKenzie, Brent S; Andrews, Arna E.

J Immunol ; 197(11): 4392-4402, 2016 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-27807194

19.

Limbic.

Wicks, Ian P.

Ann Intern Med ; 175(11): 1621, 2022 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-36375161

20.

A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean Fever.

Moghaddas, Fiona; Llamas, Rafael; De Nardo, Dominic; Martinez-Banaclocha, Helios; Martinez-Garcia, Juan J; Mesa-Del-Castillo, Pablo; Baker, Paul J; Gargallo, Vanessa; Mensa-Vilaro, Anna; Canna, Scott; Wicks, Ian P; Pelegrin, Pablo; Arostegui, Juan I; Masters, Seth L.

Ann Rheum Dis ; 76(12): 2085-2094, 2017 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-28835462

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Instituto Evandro Chagas

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